SB 205384, solid

Code: S7936-5MG D2-231

Application

SB 205384 was used to study GABA-gated currents in rat locus coeruleus neurons.6

Biochem/physiol Actions

SB 20538...


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Your Price
£197.00 5MG
Discontinued
£236.40 inc. VAT

Application

SB 205384 was used to study GABA-gated currents in rat locus coeruleus neurons.6

Biochem/physiol Actions

SB 205384 is a selective and positive allosteric modulator of non-benzodiazepine site of the GABAA receptor.3 It affects the extrasynaptic GABAA receptors in rat cortical neurons4 and enhances the GABAergic transmission onto pro-opiomelanocortin neurons in mice.5

GABAA receptor modulator selective for the α3β2γ2 subunit combination.

Legal Information

Manufactured and sold under license from GlaxoSmithKline Pharmaceuticals

coloroff-white
formsolid
InChI keyJDTZAGLGBRRCJT-UHFFFAOYSA-N
InChI1S/C17H18N2O3S/c1-3-4-7-22-17(21)13-9(2)19-16-14(15(13)18)11-6-5-10(20)8-12(11)23-16/h10,20H,5-8H2,1-2H3,(H2,18,19)
Quality Level100
SMILES stringCC#CCOC(=O)c1c(C)nc2sc3CC(O)CCc3c2c1N
solubilityDMSO: 18 mg/mL, H2O: insoluble
Cas Number160296-13-9
This product has met the following criteria to qualify for the following awards:



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